May 1, 2018
May 1, 2018 —
The All of Us Research Program officially opens for enrollment Sunday, May 6. Led by the National Institutes of Health (NIH), All of Us is an unprecedented effort to gather genetic, biological, environmental, health and lifestyle data from 1 million or more volunteer participants living in the United States. A major component of the federal Precision Medicine Initiative, the program’s ultimate goal is to accelerate research and improve health.
April 2, 2018
April 2, 2018 —
The vast majority of genetic mutations associated with cancer occur in non-coding regions of the genome, yet it’s unclear how they may influence tumor development or growth. Researchers at University of California San Diego School of Medicine and Moores Cancer Center identified nearly 200 mutations in non-coding DNA that play a role in cancer. Each mutation could represent a new cancer drug target. The study is published April 2 in Nature Genetics.
March 5, 2018
March 5, 2018 —
UC San Diego School of Medicine researchers developed a visible neural network and used it to build DCell, a virtual model of a functioning brewer’s yeast cell. To do this, they amassed all knowledge of cell biology in one place and created a hierarchy of these cellular components. Then they mapped standard machine learning algorithms to this knowledgebase. DCell can be viewed at
d-cell.ucsd.edu. The technical details are published March 5 in
Nature Methods.
February 14, 2018
February 14, 2018 —
Researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health have discovered that a chemical compound that activates ATF6, a gene associated with an inherited vision impairment, also converts patient-derived stem cells into blood vessels.
February 5, 2018
February 5, 2018 —
In approximately 15 percent of cases where couples are unable to conceive, the underlying cause of infertility is not known. Researchers at University of California San Diego School of Medicine and in the Division of Biological Sciences at UC San Diego have identified a protein in mice that must be present in eggs for them to complete normal development. Without the protein, called ZFP36L2, the eggs appear ordinary, but they cannot be fertilized by sperm.
January 18, 2018
January 18, 2018 —
Catherine M. Robertson, MD, has been named chief of Sports Medicine at UC San Diego Health. Robertson, a board-certified orthopedic surgeon who specializes in treating injuries of the shoulder, knee and hip, will further enhance UC San Diego Health’s reputation for customizing innovative, evidenced-based care for all athletes — from the weekend warrior to elite, professional and Olympic athletes.
December 21, 2017
December 21, 2017 —
Every day, every inch of skin on your body comes into contact with thousands of molecules — from food, cosmetics, sweat, the microbes that call your skin home. Now researchers can create interactive 3D maps that show where each molecule lingers on your body, thanks to a new method developed by University of California San Diego and European Molecular Biology Laboratory (EMBL) researchers. The technique is published December 21 in Nature Protocols.
December 11, 2017
December 11, 2017 —
Researchers at University of California San Diego School of Medicine have found a genetic signature for delay discounting — the tendency to undervalue future rewards — that overlaps with attention-deficit/hyperactivity disorder (ADHD), smoking and weight.
December 5, 2017
December 5, 2017 —
Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.
